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Published Resources Details Journal Article
- Title
- HLA-DR RFLP distributions in two groups of aboriginal Australians
- In
- Australian and New Zealand Journal of Medicine
- Imprint
- vol. 20, 1990, pp. 790-793
- Url
- http://onlinelibrary.wiley.com/doi/10.1111/j.1445-5994.1990.tb00424.x/pdf
- Abstract
HLA-DR and -DQ typing by restriction fragment length polymorphism (RFLP) in Aboriginal Australians from the Kimberleys and from Coen shows a restricted number of HLA-DR types in these populations. The polymorphism is essentially limited to DR2, DR4, DRw14 and DRw8. The most common DR.DQ RFLP haplotype in Aborigines shows a novel arrangement of DR and DQ alleles that has important implications for histocompatibility matching if the RFLP patterns reflect functional variation in HLA class II molecules.
